In a non default environment we couldn' use a Gateway to connect to on-premise resources. It should be posible to reuse/share an existing gateway in non default envrionments to create a connection to an external database (ex. SQL Server on-premise).
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We plan to do this feature. Currently, if you have an urgent business need for this feature, we can whitelist your non-default environment to allow gateway. You need to file a support ticket for this and we will evaluate carefully your request.